Describe the pathway used by cells to place carbohydrates on plasma membrane proteins.?
Question by Isabel P: Describe the pathway used by cells to place carbohydrates on plasma membrane proteins.?
Explain why this pathway results in the carbohydrate grouops being on only one side of the lipid bilayer.
Answer by apclass123
Well, smooth endoplasmic reticula are involved with glycolysation of membrane proteins, but
here’s how that would work. First, the membrane protein would be made in the rough endoplasmic reticulum. The protein would be fused to the membrane of the rough endoplasmic reticulum,
then, as a vesicle, it would travel to the smooth endoplasmic reticulum where the carbohydrate would be added. The glycoprotein would then be fused to the membrane of the smooth endoplasmic reticulum, then as a vesicle, it would travel to the Golgi apparatus. The Golgi complex would then “package” and “label” the glycoprotein so it would arrive at the cell membrane and not at another organelle, and also so the protein will not be excreted (I believe). The vesicle would then fuse with the cell membrane and thereby become a membrane glycoprotein.
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